"The IMHA core package was responsible for my 14 year old dachshund Rusty being able to stabilize and recover. At start of treatment Rusty was weak and needed help to stand.... after starting the protocol he was much brighter and able to stand up on his own and walk around." Tracy Brown

IMHA Package for Dogs and Cats

Size *

Our Immune Mediated Hemolytic Anemia Package consists of the four supplements for dogs and cats that we consider to form the foundation of our Natural IMHA Protocol. This supplement package for dogs and cats with IMHA is a research-based protocol developed by a certified Master Herbalist working alongside a certified Canine Nutritionist. It is the most complete supplement protocol that supports dogs and cats with immune mediated hemolytic anemia* and from the feedback we receive we conclude the most successful available. It has taken more than a decade of experience working with animals to assemble.

This supplement package for IMHA consists of the supplements Immune Balance, BioPreparation F3, Daily Multi Plus and ChlorOxygen. You may follow the links to view the product pages for more information on these supplements for your dog or cat with immune mediated hemolytic anemia as well as individual product ingredients. This is not an inexpensive protocol, however IMHA is a serious condition and we have incorporated many years of research and experience working with animals to develop this IMHA protocol for your dog or cat and we hope you are pleased with the results.

For further information about this condition please view our Natural Immune Mediated Hemolytic Anemia Protocol. You may select from our list of other recommended supplements for dogs and cats with IMHA that can be found on our immune mediated hemolytic anemia page to use in addition to our Core Package or rely on these four supplements for IMHA alone. We are here to help so feel free to Contact Us if you need more assistance.

The Core IMHA Package is designed to provide the supplements for your dog or cat with immune mediated hemolytic anemia to get you started. You will not need to purchase the entire package at the same time again. Instead, you will purchase individual supplements/herbal remedies as you need them because they last varying lengths of time. You can also purchase larger sizes of the supplements/herbal remedies as larger sizes have discounts incorporated into their cost.

Core IMHA Package Sizes

Small Package (Recommended for animals up to 25 lbs)

Biopreparation F3+ Forte - 60 Caps (*will last 120 days (5 lbs) to 60 days (25 lbs))
Immune Balance - 2 oz (60 ml) (*will last 120 days (5 lbs) to 30 days (25 lbs))
Daily Multi Plus - 3.5 oz (99 gram)(*will last 250 days (5 lbs) to 50 days (25 lbs))
ChlorOxygen - (one ounce bottle provides approximately 900 drops)

Medium Package (Recommended for animals 25 - 50 lbs)

Biopreparation F3+ Forte - 60 Caps (*will last 60 days (25 lbs) to 30 days (50 lbs))
Immune Balance - 4 oz (120 ml) (*will last 60 days (25 lbs) to 30 days (50 lbs))
Daily Multi Plus -  3.5 oz (99 gram) (*will last 50 days (25 lbs) to 25 days (50 lbs)
ChlorOxygen - (one ounce bottle provides approximately 900 drops)

Large Package (Recommended for animals 50+ lbs)

2 - Biopreparation F3+ Forte - 60 Caps (*will last 60 days (50 lbs) to 60 days (100 lbs)
Immune Balance - 8 oz (240 ml) (*will last 60 days (50 lbs) to 30 days (100 lbs))
Daily Multi Plus - 12 ounces (340 gram) (*will last 85 days (50 lbs) to 42 days (100 lbs)
ChlorOxygen - (one ounce bottle provides approximately 900 drops)

*Time frame estimates above use minimum suggested serving size and can vary depending on animal weight and serving size/frequency used.

Core IMHA Help Sheet for Dogs and Cats

A copy of this information is included with your package purchase!

1). Daily Multi Plus

This is the supplement that provides the enzymes and probiotics necessary for proper digestion and immune system health. It also provides organic, whole food nutrition to improve the overall health of your dog or cat.

How much should I give?

Provide 1/2 teaspoon in each meal per 30 lbs. Mix with water so it is not dry. Serving size does not have to be exact. Err on the side of more rather that less.

How long should I provide this supplement?

This supplement should be given with every meal for the life of your pet.

2). Biopreparation F3

This is a highly regarded supplement vital to your animal’s recovery. We recommend the F3+ Forte for this condition. It feeds cells on a cellular level providing thousands of natural nutrients directly into cells without the need for digestion while helping cells to efficiently detoxify. This can be placed in with meals, a little meatball made with a favorite food or in a little water used with a syringe. Follow the recommendations below for the Acute Phase and then when your animal’s condition has stabilized in the “normal” range continue with the Maintenance Phase for the life of your animal.


Acute Phase

Maintenance Phase

Under 15 lbs

1/4 capsule every 2 hrs for a total of 1 1/2 - 2 capsules daily

1/2 capsule 2x daily

15 - 30 lbs

1/2 capsule every 1 - 2 hours for a total of 2 1/2 - 3 capsules daily

1/2 - 1 capsule 2x daily

30 - 50 lbs

1/2 capsule every 1-2 hours for a total of 4 - 5 capsules daily

1 capsule 2x daily

Over 50 lbs

1 capsule every 2 hours for a total of 5-6 capsules daily

1 capsule 2x daily and you may add a third capsule daily.

3). ChlorOxygen

This supplement is rich in chlorophyll that contains a compound that increases the health of red blood cells and greatly increases their oxygen carrying capacity. This could make the difference between life and death for your animal. Remember the directions on the bottle are for people so use the serving suggestions below.

How much should I give?

Use 2 - 4 drops per 10 lbs 4x daily while your animal is in the acute critical phase.

How long should I provide this supplement?

When your animal is stable in the “normal” range provide a maintenance dosage of 2 drops per 10 lbs twice daily for the life of your animal.

4). Immune Balance

This remedy is used to help balance your animal’s immune system in the presence of an autoimmune condition. It can work with the medications you may be receiving from your vet or on its own and can help support your animal’s liver as well.

How much should I give?

Provide 1 ml per 25 lbs three times daily. Squirt directly into mouth by pulling out lower lip at corner of mouth. Do not tilt head back because your pet can breath some in. If this is difficult dosage can be placed in a small amount of special food or even main meals if necessary. It is best to give away from meals when possible. When your animal’s condition improves you may be able to reduce the frequency to two times daily.

How long should I provide this supplement?

This can be used long term on a five days on two days off schedule or you can discontinue use when your animal is fully recovered and their RBC numbers stay up even when they are weaned off of the Immune Balance in the future. The length of time your animal stays on this remedy depends on the situation which is unique to you. Do not use or use with caution in animals with hypertension

Other Recommendations


We recommend a simple whole food diet during the critical phase consisting of calf liver (blood building) mixed in scrambled eggs with liquified greens (lettuce liquified in blender with a little water). Meals should be small and spaced four or five times throughout the day. When your animal has improved and is stable you can move to a regular commercial whole food diet (preferably raw) or a home cooked diet (research how to do this properly and make sure to add a calcium source). There is also the option to use prepackaged premixes to which you add your own meat. Read our articles How to Feed Your Dog or How to Feed Your Cat in the Education Section of our website for more information.


Exercise should be limited during the acute phase until your animal is very stable. This is because your animal’s oxygen carrying capacity is greatly diminished and exercise can place potentially dangerous stress on your animal.

About Medications

Immune suppressing drugs and blood transfusions can be life-saving at the critical phase for your animal. It is hard for us to make recommendations concerning medications because it is really out of our “jurisdiction” and all animals and situations are so unique. What we do feel comfortable saying is that as time progresses these medications (especially drug “cocktails”) can have severe and even potentially life-endangering side effects over time that could negatively effect the recovery of your animal. Veterinarians may be afraid and resistant to removing medications, and maybe rightfully so depending on the situation. However, we feel that leaving your animal on medications out of fear can be counter-productive. From our experience medications should be adjusted as your animal stabilizes to see what can be removed in the shortest time frame possible without risking the health of your animal.

Common Causes

Nothing “just happens”. There is always a catalyst. Autoimmune conditions are caused by an insult to the body, most commonly from a chemical or toxin. Flea and tick pesticide treatments are a major cause. Reactions will be seen within hours or days of application. Vaccinations are another major cause with reactions generally seen anywhere from days to months after exposure. But if your animal is more sensitive household cleaners, lawn chemicals, mosquito fogging exposure and even skunk spray can trigger this condition. Please keep in mind that once an animal develops IMHA experiencing a relapse if exposed to any of the above is very common. Speak with your veterinarian about an exemption from future rabies vaccinations.

Please Note:

The majority of our supplements are basically herbs and whole foods, so a little more or less will not harm your animal. When determining the dosage estimate as best you can for the weight of your animal from our suggested serving sizes.

These statements have not been evaluated by the Food and Drug Administration.These products are not intended to diagnose, treat, cure or prevent any disease.

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