"My little fur girl became very ill in May of 2018, she was diagnosed with IMHA and a red blood cell count of 12. A "specialist" told me she should be put down. After starting the BioPreparation regiment she started to make gradual improvements and soon was off all the drugs with red blood cell counts between 45 & 50!" Shawn N

BioPreparation F2 F3 for Dogs and Cats

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BioPreparation is more than just a spirulina supplement for dogs and cats. It is a blend a FOUR microalgae strains, chosen from thousands, that make this supplement FAR superior to ordinary synthesized vitamin & isolated mineral supplements(1)! Biopreparation F2 Core & F3 Forte are the original nutritional formulas for pets from research scientists at Bionutrition, with over 20 years of research, development and testing on over 20 different animal species. An all-natural, whole food supplement created with four of the most nutrient dense algae found on earth, BioPreparation is grown in a controlled, organic, hydroponic environment using mineral rich volcanic thermal fluid as the water source.

This controlled hydroponic environment maximizes the nutritional value of the algae in this formula(2) while virtually eliminating contaminants. Very different when compared to ordinary pond grown spirulina supplements (FYI - typical organic spirulina supplements have the same amount of heavy metal contaminants as regular spirulina!). Because Biopreparation is a blend of four algae species, this amazing microalgae supplement provides balanced and synergistic whole food nutrition and powerful healing effects for dogs, cats and other animals.

However, perhaps the most amazing benefit of the microalgae in Biopreparation is their ability to provide direct cellular nutrition. This means they can feed the cells of your dog or cat without the need for digestion - they just cross the digestive tract to feed cells directly! This means they can also cross the blood-brain barrier to feed the hypothalamus as well as the blood-retinal barrier to keep your pet's eyes healthy!



BioPreparation's thousands of nutrients occur in their pristine natural form that an animal's body recognizes (unlike synthetic vitamins!). BioPreparation is a Whole Food breakthrough in holistic pet nutrition with over 5,000 naturally occurring nutrients and the algae it contains are often promoted as superfoods(3)!

Led by Professor Michael Kiriac, PhD., N.D., the Science Academy of the former Soviet Union deployed over a thousand person-years of intensive research efforts to produce bio-algae concentrates that hold extraordinary nutritional properties. Consisting of blends of the best algae from over 35,000 available on earth, these concentrates have been clinically proven and used in animal and human applications for over 20 years.

The BioPreparation and BioSuperfood formulas are certified under the Health Canada Natural Product program. The algae in these formulas are nurtured and harvested in a hydroponic pure environment, protected from pollutants, free of herbicides and pesticides, and blended, encapsulated and bottled under strict quality control. The algae are protected with a proprietary freeze-drying technology that preserves the nutrients 100%.

  • The Formulas are kosher and vegan

  • Protected from pollutants

  • Guaranteed free of herbicides and pesticides

  • The formulas are certified under Health Canada Natural Product

BioPreparation Formula F2+ Core

BioPreparation formula F2+ Core is suggested for general nutritional support of the immune system and as a replacement for many commercially available supplements with the usual synthetic vitamins and isolated minerals. It is also recommended for increased vitality, strength and endurance for general activity. Note: this formula was the original formulation developed for animal research in Russia.

Possible benefits

  • Healthier teeth, skin, coat, nails and hair

  • Natural, safe and simple anti-aging

  • Muscle mass gains remain longer

  • Increased endurance and stamina

  • Faster recovery from exertion

  • Balanced blood-sugar levels

  • Overall biochemical balance

  • Natural energy boost

  • Boosted immunity and free-radical shield

  • Increased protection and prevention

BioPreparation Formula F3+ Forte

BioPreparation formula F3+ Forte offers advanced nutritional support for the immune system and increased vitality for healthy aging. We recommend this formula for most dogs and cats with chronic conditions that need more concentrated cellular nutrition.

  Possible benefits

  • All the benefits from Formula F2+ plus:

  • Advanced protection and prevention

  • Reduced inflammation and faster recovery time

  • Restored overall biochemical balance

  • Natural long-lasting energy boost

  • Increased metabolic recuperation and regeneration

  • Powerful immune system support

How BioPreparation Works

As per Hippocrate's advice: "let thy food be thy medicine", good foods have the potential to nourish and heal. For this healing to be a reality, the nutrients in our food must be absorbed within our cells in sufficient quantities. With poor food choices, aging, and other metabolic deficiencies, this absorption becomes quite inefficient and cellular disease takes over. Due to its extraordinary broad nutrient content and bioavailability, BioPreparation's nourishing potential is much higher than that of ordinary foods and other supplements.

In addition, this formula has a dramatic effect on the brain! Specifically the hypothalamus and pineal glands that are responsible for the regulation of all physiological metabolisms. This includes the sympathetic and parasympathetic nervous system, the central nervous system, the lymphatic system, the cardiovascular system and the digestive system. This is where all healing and systemic maintenance and repair begins and this is why BioPreparation can have such a powerful effect on your pet's health!

BioPreparation Benefits

  • Contains Over 4,000 Enzymes

    Cooked food (canned and dry kibble) lacks enzymes because heat kills live enzymes. Your animals need enzymes daily to digest foods. Feeding your pet processed foods every day leads to depletion of live enzymes. Without enzymes pets age faster and are plagued with degenerative diseases such as arthritis, cancer, irritable bowel syndrome, diabetes, etc.

  • Formulated by Nature

    To get required nutrients, animals in the wild instinctively consume algae when they drink from natural water sources (e.g. pond or stream). Our domesticated pets, fed processed foods and tap water, do not get algae and therefore are deficient in many nutrients like: protein, enzymes, essential fatty acids, vitamins, minerals and trace elements. Feeding BP to our animal companions provides them the daily essential nutrients they need in the natural form and dosage that nature intended.

  • BioPreparation is a Whole Food Supplement

    BioPreparation is a whole food supplement that is safe, naturally occurring, balanced and complete with thousands of natural enzymes in a form easily assimilated by your animal's body unlike most isolated or synthetic compounds found in other supplements. BioPreparation is not, and far from, a conglomeration of separate, isolated vitamins and minerals or extracted and concentrated ingredients bound together and compressed with fillers into a pill.

  • Superior Immune System Support

    Poor immune system, degenerative conditions and diseases, and a shorter life span are all indications of sub-standard nutritional diets (dry kibbles and canned food). BP helps give back to your pets the health nature intended them to have.

  • The microalgae in BioPreparation formulas are nurtured and harvested in a controlled hydroponic environment, protected from pollutants and guaranteed free of herbicides and pesticides. They are further blended, encapsulated and bottled under strict quality control. The nutrients are protected with advanced freeze-drying technology that preserves 100% of the nutrients for many years.

  • The formulas are Kosher and Vegan.

BioPreparation Details

Available in a container with 60 capsules.

BioPreparation is a special blend of microalgae, the oldest form of food on the planet. Fossils exist of cyanobacteria blue-green algae that are over 3.5 billion years old. There are over 70,000 algae species or types of algae in the world. Some are magnificent whole foods such as spirulina and dunaliella as contained in BioPreparation.

There are thousands of known nutrients in BioPreparation, and many unknown.
BioPreparation is a blend of four, whole microalgae (whole as in whole food), each containing thousands of nutrients that are seen under the microscope or detected with the latest laboratory equipment. As with some fruits and vegetables, in BioPreparation's microalgae, there are hundreds and possibly thousands more phytonutrients that are too small to be seen with their current microscopes and technologies, but that will be identified in the years to come. For example, a few decades ago they identified lycopene in tomatoes even though it had been present in tomatoes for thousands of years.

Nutrients Found in Biopreparation for Dogs & Cats

Nutrient Profile

    • Complete Protein Makeup

The algae in these blends have minimal cellulose in their cell walls, being composed of soft mucopolysaccharides. Their proteins are 85% to 95% digestible, far more than meat and fish (15-25%), soybeans (35%), dried milk (35%), peanuts (25%), eggs (12%), grains (8-14%) or whole milk (3%). This high digestibility rate is especially important for animals and people suffering from intestinal malabsorption problems which is very common nowadays. The elderly have even more difficulty digesting complex proteins, and many are on restricted diets.

    • Amino Acids

Contains 20 amino acids; all eight to ten essential and 12 non-essential amino acids in high availability or non limiting form.

    • A Complete Range of Naturally Occurring Vitamins

These formulas contain the array of vitamins that most living beings need to carry on metabolic processes. Not only do they contain all vitamins, including a full Vitamin B Complex, vitamins A, D, K, E & C, BUT also contain all co-dependent nutrients for these vitamins to be functional and active for proper assimilation.

    • Minerals

There are more then 100 dietary minerals and trace elements detected in each of these formulas. But when using specific element analysis, some amount of all known dietary minerals can be detected! Minerals are constituents of the bones, teeth, soft tissue, muscle, blood, and nerve cells. They are vital to overall mental and physical well-being. Minerals act as catalysts for many biological reactions within the body, including, muscle response, the transmission of messages through the nervous system, and the utilization of nutrients in food.

    • Trace Elements

Contain some amount of all known trace elements occurring in a most animal/human friendly form, that is naturally occurring from the plant kingdom. In biochemistry, a trace element is a chemical element that is needed in minute quantities for the proper growth, development, and physiology of the organism. For this reason, in biochemistry they are also called micro nutrients.

    • Enzymes

These formulas contain thousands of enzymes! We believe that no other food or combination of foods contains so many naturally occurring enzymes. Some of these enzymes are critically important for health, such as superoxide dismutase (SOD). SOD is an iron-containing enzyme that supports important body-cell processes and also protects the cells from free radicals. Enzymes are specialized protein molecules facilitating most of the body's metabolic processes - such as, supplying energy, digesting foods, purifying your blood, ridding the body of waste products etc.

    • Fatty Acids

Contain Omega 3, 6, 9, GLA and several more including some yet undocumented or undiscovered. Most of us think of fatty acids as oils coming from fish or seeds. You will be happy to learn that these formulas are a rich source and especially high in GLA, which is a critical nutrient that is universally lacking in the American diet.

    • Chlorophyll

Spirulina in these formulas is one of the richest sources of chlorophyll with a perfect balance of magnesium. All plants, algae, and cyanobacteria (blue-green algae) which photosynthesize, contain chlorophyll usually with the proper balance levels of magnesium required for photosynthesis. Chlorophyll is sometimes called "green blood" because of its similarity to the hemoglobin molecule found in human blood cells. In fact, both are constructed of almost identical molecular structure called pyrrole rings, and both substances are chemically known as "porphyrin pigments" by scientists. In addition, there's nothing more supportive to cleansing than chlorophyll. And people who follow Western diets (high in processed foods and animal foods) are in desperate need of cleansing.

    • Polysaccharides

The algae found in these formulas have unique cell wall made of complex polysaccharides, which have been shown to stimulate interferon production and exhibit strong anti-tumor activity in a series of studies conducted over the last several decades.

    • Phytonutrients

These formulas with their mix of blue-green, brown and red microalgae contain thousands of phytochemicals and colorful pigments making up the entire color spectrum found in nature from blue to green and red. We know today that the principal nutrients for prevention of cancers are found in colorful fruits and vegetables (American Cancer Society). Those nutrients are the mixed of phytonutrients such as antioxidants, carotenoids, chlorophils and other compounds found in those fruits and vegetables and especially concentrated in BioPreparation and BioSuperfood formulas.

    • Antioxidants

Contain extraordinary antioxidant compounds and especially those like alpha-carotene and beta-carotene known as "pro-pro vitamin A" for their capacity to not only traverse cell membrane but to span across the cell membrane. An antioxidant is a molecule capable of slowing or preventing the oxidation of other molecules. Oxidation is a chemical reaction that transfers electrons from a substance to an oxidizing agent. Oxidation reactions can produce free radicals, which start chain reactions that damage cells. Antioxidants terminate these chain reactions by removing free radical intermediates, and inhibit other oxidation reactions by being oxidized themselves.

    • Carotenoids

These formulas contain an extraordinary number of yellow/orange pigments called carotenoids. Carotenoids are organic pigments that are naturally occurring in plants and some other photosynthetic organisms like algae, some types of fungus and some bacteria. The extraordinary amounts of carotenoids and several lesser pigments such as phycoerythrin, tetrapyrrole, and phytonadione found in these algae are not just the "color" of living organisms, but are used to carry on metabolic processes throughout the body. Without them, enzymatic reactions would be reduced until cellular disintegration occurred.

Health Benefits of Carotenoids for Dogs & Cats


Bio Nutrition. Retrieved from https://bionutrition.com/

Biopreparation Ingredients. Retrieved from https://bioage.com/ingredients/

Hoffman, D. (2003). Medical herbalism: The science and practice of herbal medicine. Rochester, VT: Healing Arts Press.

Murray, M. T., & Pizzorno, J. E. (1998). Encyclopedia of natural medicine (2nd ed.). New York, NY: Three Rivers Press.

Pitchford, P. (2002). Healing with whole foods: Asian traditions and modern nutrition (3rd ed.). Berkeley, CA: North Atlantic Books.

It is important to note that these four species of algae were chosen out of tens of thousands of microalgae species. When combined they provide powerful, synergistic cellular nutrition.

*Please keep in mind that the algae in this formula are grown in an indoor, controlled environment free of pollutants. So, although you may find information online that algae such as these can be contaminated because they are usually grown in outdoor ponds, this is not the case for the microalgae in Biopreparation.

Spirulina Pacifica and Platensis for their large protein and mineral values

Spirulina Microalgae in Biopreparation


These formulas contain two species of Spirulina; Spirulina Platensis and Spirulina Pacifica. Spirulinas are blue green micro-algae, unseen to the naked eye, usually grown in warm and brackish water. It contains between 60 to 70% complete and highly digestible proteins. Its protein makeup contains 18 to 22 amino acids, including all the 8 essential amino acids. Spirulina is a rich source of vitamins A, B, E, H, and of thousands of enzymes, dozens of minerals and trace elements, and chlorophyll.

They are also one of the best sources of Gamma Linolenic Acid (GLA) – an essential fatty acid necessary for tissue growth and regeneration. Due to its soft cell wall all of Spirulina’s nutrients are easily assimilated.

When blended together, Platensis and Pacifica offer the entire family of amino acids and more minerals/ trace elements, vitamins, fatty acids and enzymes (gram for gram) than any other food on earth(4).

Dunaliella Salina for its extraordinary mix of carotenoids

Dunaliella Salina Microalgae in Biopreparation


Dunaliella Salina is a single celled, salt-water micro-algae that under appropriate growth conditions can accumulate large amounts of beta-carotene and other carotenoids. Dunaliella contains other carotenoids such as alpha carotene and xanthophylls like zeaxanthin, cryptoxanthin and lutein. It also accumulates very high concentrations of glycerol.

High concentrations of beta-carotene and glycerol offer Dunaliella protection from the saline conditions and osmotic pressure of the environment where it lives. Natural mixed carotenoids found in Dunaliella salina are among nature's best antioxidants (5).

Haematococcus Pluvialis for its high content in astaxanthin

Haematococcus Pluvialis Microalgae in Biopreparation


Haematococcus Pluvialis is the world's highest source of astaxanthin(6), a unique natural carotenoid pigment and an extremely powerful biological antioxidant. A growing body of scientific literature shows that natural astaxanthin surpasses by far the antioxidant benefits of vitamin C and vitamin E (7).

Astaxanthin holds superior antioxidant activity and has an ability to support and maintain natural inflammatory response. Additionally, scientific research has proven that astaxanthin is able to cross the blood-brain barrier and the central nervous system better than many other antioxidants.

Other Ingredients: Vegetarian Gelatin, Water and Glycerin. Please notice that there are none of the usual synthetic additives found in most other capsules and tablets.

Serving suggestions can be found in the table below. It is often recommended for chronic conditions that you wait four days in between additional servings. For example, if your dog is 15 lbs you would provide 1/2 capsule in morning meal, wait four days and then add the second 1/2 capsule serving in the evening meal for a total of 2x daily. In serious, acute conditions like IMHA this is disregarded due to the seriousness of the condition and all recommended servings are started on the first day.

Weight Chronic Condition Acute Condition
Under 15 lbs Dogs: 1/2 capsule 2x daily. Cats/Very Small Dogs: 1/4 capsule 2x daily
Dogs: 1/4 capsule every 2 hrs for a total of 1 1/2 - 2 capsules daily. Cats/Very Small Dogs: 1/8 capsule every 2 hrs for a total of 1 - 1 1/2 capsules daily
15 - 30 lbs 1/2 - 1 capsule 2x daily 1/2 capsule every 1 - 2 hours for a total of 2 1/2 - 3 capsules daily
30 - 50 lbs 1 capsule 2x daily 1/2 capsule every 1-2 hours for a total of 4 - 5 capsules daily
Over 50 lbs 1 capsule 2x daily and you may add a third capsule daily 1 capsule every 2 hours for a total of 5-6 capsules daily


More verbose guidelines are provided below if you are interested:

These usage guidelines have been composed based on information gathered from years of empirical research conducted or managed by Dr. Michael Kiriac in the U.S.S.R. from the years 1973 to 1996, from use and research conducted in Canada since 1996, and more recently from input of practitioners and customers both in Canada and in the U.S.A. about their usage of BioPreparation with animals.

Holistic Usage

If one wants to use BP as per Hippocrates’ advice “Let thy food be thy medicine”, then one must let go the palliative mindset (a specific remedy for a specific symptom) in favor of the holistic approach (remedy aimed at the whole of health and the root cause of the symptom). Transitioning from our palliative training to the holistic one involves faith, trust, wisdom and experience. Faith and trust are innate while wisdom and experience are acquired. The holistic approach in the context of BP means that you are going to nourish the body a certain quantity of BP in order to derive whole body benefits which include energy, growth, repair, cleansing, protection and regeneration or cell splitting.

With food “no one food or quantity of a food fits all”, and as per any other diet or nutritional program, flexibility and respect of individual biochemistry is recommended. In general, for health maintenance and prevention, one can feed an average size pet anywhere from a pinch up to 3 capsules per day (of a single formula or a mix of formulas) depending on the animal specie, its size and several factors and on each animal case by case:

  • selected nutritional support program objectives and goals – i.e. nutrition, remedial, performance

  • animal unique biochemistry, adaptation and sensitivity

  • other program underway (medication, supplements, etc)

  • may vary based on need (or not) for speed

  • multiple parallel objectives

For more advanced nutraceutical use, you may contact us for suggestions.

Selection of formula(s) and quantity of capsules/amount per day

The first thing to consider when using BP is that “you have to eat some to derive benefits”. BP is a micro food with mega nutrients which delivers more or less nutritional results and benefits base on the quantity consumed. There are two BP formulas, and each one contains the four algae and their thousands of nutrients occurring in different proportion or distribution. Due to these differences, each formula results in nutraceutical value and beneficial effects.

General Suggestions

  • Even when there is more than one Formula to give, as much as possible, feed no more than one capsule at a time, scheduled every few hours starting first thing in the morning until reaching the total capsules for the day. For larger animals like a horse or cow, it is OK to give two capsules at one time.

  • When 2 formulas are suggested, alternate each formula. When the total capsules for one formula are finished, continue with the remaining capsules for the second formula.

  • Though not required, you may feed capsules alongside meals or snacks.

  • Water is important for animals eating BP. Use filtered water without chloride. It is important to ensure the animal drinks plenty of water as to avoid dehydration. In some instances, to accomplish this, one can sprinkle a small amount of sea salt on their food to make them thirsty or add lots of water to their food and monitor their water intake.

  • Avoid commercial dry foods; look for fresh wet and raw real meat.

  • For pets, feed the animal at least 50% of raw foods

  • Feed the animal with organic food as much as possible

  • Where appropriate, exercise the animal frequently.

  • Allow the animal to be in the sun daily 30 to 60 minutes - early morning and late afternoon.

  • Modifications to program due to reactions are normal and can be different for every animal and condition.

  • Mix BP powder well with food/feed or feed directly, but make certain it is ingested.

  • For high performance goals, degenerative conditions, injuries and other health issues: Augment the number of capsules as well as introduce F3+ when required. A protocol for these goals, objectives and conditions can be obtained from your professional that introduced BP.

Durations of Use

Duration of use may vary depending on specifics and conditions, frailty or other issues with each animal. Generally, degenerative conditions that took years to settle in will require between 3 to 6 months of the initial program suggested. Following the initial program, a lifetime maintenance program of at least a pinch (for very small) to 1 capsule of F2+ per day will be recommended. Often with nutritional supplements, one may observe early results or no results, and decide to stop the program prior to achieving the desired results. It is recommended to follow through with the program until the goals are achieved.

Adaptation Mode

Because of the nutraceutical benefits of the products, as with any dietary changes, it is suggested to start giving the product gradually to allow nutritional changes to take place gradually within the body and be well received by the animal. Select from the Adaptation Modes below the appropriate mode based on the health condition and/or desired goal for the animal.

Start with one dose per day of each suggested formula; increase the dose for each suggested formula every two (2) to three (3) days until you reach the suggested total dosage per day.

Slow - Start giving 1 dose per day of each suggested formula; increase the dose of each formula suggested every four (4) to six (6) days until you reach the suggested total dosage per day.


With condition of high blood pressure, brain injury, thyroid condition, pregnancy, fragile intestine and any other serious or fragile health condition, it is important to start the program in Slow mode.


BP is micro-food and will combine well with other vitamins, herbs, greenfood and diets. There are no known contra-indication with drugs.

Suggestion of Usage by Species

Maintenance: 1/3 to 1 capsules of F2+ between 1 to 3 times per day.
Advanced: 1/3 to 1 capsules of F3+ between 1 to 3 times per day.

Maintenance: 1/3 to 1 capsules of F2+ between 1 to 2 times per day.
Advanced: 1/3 to 1 capsules of F3+ between 1 to 3 times per day.

Cow and beef
Maintenance: 1 capsule of F2+ two to three times per day.
Advanced: 1 capsule of F3+ one to two times per day.
Note: Dairy cows protein feed will need to be reduced by ~1.25 lb gradually over the first four weeks.

Horse and Pony
Adaptation: 1 capsule each of F2+ and F3+ twice per day for two weeks.
Maintenance: 1 to 2 capsules of F2+ twice per day.

Goat and Sheep
Maintenance: 2 capsules of F2+ per day - one AM and one PM

Maintenance: 3-4 capsules F2+ per 1.5 kg of feed. First mix well 2 capsules with two handfuls of feed, then mix well the resulting two handfuls feed with ¼ of the remaining feed, and then mix well this resulting feed with the balance of the feed.
Notes: A 20% productivity increased was observed in the poultry at the Moldavian research center, with better essential amino acids, albumin and fat content, reduction of diseases and mortality while not using antibiotics, resulting in healthier and better tasting meat. BP helps with the essential assimilation of calcium so important for the bone mass and the egg shell, while allowing for larger eggs.

Ferret, Mink, Rabbitt
Maintenance: 1/3 capsules of F2+ three to four times per day

Maintenance: a pinch to 1/3 capsules of F2+ twice per day - one AM and one PM

Bird (small birds)
Maintenance: 1 capsule F2+ mixed to one day feed for 10 small birds
Note: Mix well with feed, to avoid loss of product.

Fish (small pet fishes)
Maintenance: a pinch to 1/2 capsule F2+ in water to feed up to 50 small fishes per day.

After a day or two, animals will get used to the smell and taste of BP and instinctively will look for the algae powder in their food.

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