Answer
Jan 09, 2026 - 03:00 PM
Yes, our Digestive Enzymes and Probiotics supplement is safe for your dog with SIBO. Don't get too caught up in worrying about probiotics that are "pro-histamine" as other strains are histamine-degrading so they balance each other out in a formula with multiple strains of probiotics. The largest contributors causing too much histamine include food (fermented & processed foods and certain produce), certain medications like NSAIDs and things like alcohol and chocolate which your dog won't be eating. These things interfere with the activity of the enzyme Diamine Oxidase (DAO) that normally breaks down histamine in the gut. Ways to improve the health of the digestive tract include a digestive enzymes supplement to help properly break down food so it doesn't ferment. Also providing probiotics to help improve the health of the digestive tract to reduce bloating and gas. Research has shown the certain spore-forming bacteria like Bacillus coagulans found in our Microbiome Harmony supplement can help to improve the health of dogs with SIBO. You can use this along with our Digestive Enzymes and Probiotics supplement. You may wish to start out slowly with new supplements that contain probiotics to limit side effects that can occur as the digestive tract rebalances. You may also wish to keep a container of our Diarrhea Relief on hand so you have it if needed. The majority of commercial pet food diets are very high is starches and these can imbalance the digestive tract and feed bacteria associated with the symptoms of SIBO. For this reason a healthy diet focused on protein and low in carbohydrates can greatly help dogs with SIBO. This diet can be home-prepared, a premix to which you add your own meat or a commercially prepared whole food diet. We offer suggestions in our article How to Feed Your Dog.
