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Core Degenerative Myelopathy Pkg


Our Core Degenerative Myelopathy Package consists of the four supplements for dogs that we consider to form the foundation of our Natural Degenerative Myelopathy Protocol. It consists of our supplements Myelin Sheath Glandular, Nerve Tonic, Immune Balance and our Daily Multi Plus. You may follow the links to view the product pages for more information on these supplements for your dog with DM as well as individual product ingredients. This is not an inexpensive protocol, however, this is a serious condition and we have incorporated many years of research and experience working with animals to develop this degenerative myelopathy protocol for your dog and we hope you are pleased with the results!

For further information and an educational video please view our Natural Degenerative Myelopathy Protocol. You may select from our list of other recommended supplements for dogs with DM, that can be found on our Degenerative Myelopathy page to use in addition to our Core Package or rely on these four supplements for DM alone. We are here to help so feel free to contact us by phone toll free at 888-683-3339 during normal business hours or email by using our Contact Us page if you need more assistance.

The Core DM Package is designed to provide the supplements for your dog with degenerative myelopathy to get you started. After this initial purchase you may wish to purchase supplements individually as they each will last varying lengths of time. You may purchase the largest DM supplement package below if you desire as there are discounts built in as you move up in size.

Core Degenerative Myelopathy Package Sizes

Small Package (Recommended for animals up to 25 lbs)

Myelin Sheath Glandular - 120 caps (2-4 caps daily)
Nerve Tonic - 2 oz (60 ml) (3 ml daily per 25 lbs)
Immune Balance - 2 oz (60 ml) (3 ml daily per 25 lbs)
Daily Multi Plus - 3.5 oz (99 gram) (Approx. 2 grams per 30 lbs daily)

Medium Package (Recommended for animals 25 - 50 lbs)

Myelin Sheath Glandular - 120 caps (2-4 caps daily)
Nerve Tonic - 4 oz (120 ml) (3 ml daily per 25 lbs)
Immune Balance - 4 oz (120 ml) (3 ml daily per 25 lbs)
Daily Multi Plus -  3.5 oz (99 gram) (Approx. 2 grams per 30 lbs daily)

Large Package (Recommended for animals 50+ lbs)

Myelin Sheath Glandular - 120 caps (2-4 caps daily)
Nerve Tonic - 8 oz (240 ml) (3 ml daily per 25 lbs)
Immune Balance - 8 oz (240 ml) (3 ml daily per 25 lbs)
Daily Multi Plus - 12 ounces (340 gram) (Approx. 2 grams per 30 lbs daily)

Degenerative Myelopathy Help Sheet for Dogs

A copy of this information is included with your package purchase!

1). Daily Multi Plus

This is the supplement that provides the enzymes and probiotics necessary for proper digestion and immune system health. It also provides organic, whole food nutrition to improve the overall health of your dog or cat.

How much should I give?

Provide 1/2 teaspoon in each meal per 30 lbs. Mix with water so it is not dry. Serving size does not have to be exact. Err on the side of more rather that less.

How long should I provide this supplement?

This supplement should be given with every meal for the life of your pet.

2). Nerve Tonic

This formula provides a highly-researched blend of nervines that help to repair and protect damaged nerve tissue as well as circulatory tonics that help to improve circulation throughout the body - from the brain to the hind quarters.

How much should I give?

Provide 1 ml per 25 lbs three times daily. Squirt directly into mouth by pulling out lower lip at corner of mouth. Do not tilt head back because your pet can breath some in. If this is difficult dosage can be placed in a small amount of special food or even main meals if necessary. It is best to give away from meals when possible. When your animal’s condition improves you may be able to reduce the frequency to two times daily. On the other hand if your animal does not respond as hoped increase the dosage by 50% three times daily.

How long should I provide this supplement?

Use daily for one month then go on a 5 days on 2 days off schedule. Use this schedule for the life of your animal. If your dog shows a decline on off days you may have to give only one day off weekly or even use daily if necessary depending on your dog’s condition.

3). Immune Balance

This remedy is used to help balance your animal’s immune system in the presence of an autoimmune condition.

How much should I give?

Provide 1 ml per 25 lbs three times daily. Squirt directly into mouth by pulling out lower lip at corner of mouth. Do not tilt head back because your pet can breath some in. If this is difficult dosage can be placed in a small amount of special food or even main meals if necessary. It is best to give away from meals when possible. When your animal’s condition improves you may be able to reduce the frequency to two times daily. If your animal does not respond as hoped increase the dosage by 50% three times daily.

How long should I provide this supplement?

Use daily for one month then go on a 5 days on 2 days off schedule. Use this schedule for the life of your animal. If your dog shows a decline on off days you may have to give only one day off weekly or even use daily if necessary depending on your dog’s condition.

4). Myelin Sheath

Myelin sheath is a glandular supplement used to support the myelin tissue and nerve transmission in dogs with DM.

How much should I give?

Provide 1 - 2 capsules daily for smaller dogs (up to 35 lbs or so) and 2 - 4 capsules for larger animals (divide into morning and evening doses). This is a food and there is no set dosage. So if your animal is doing well on the current dose fine, if not you can safely increase dosage 4 times the suggested dose especially in larger animals.

How long should I provide this supplement?

This supplement should be given with every meal for the life of your pet.

Other Recommendations


It is important dogs with DM are fed a very nutritious diet that contains high biological value protein (meat!). This can’t be accomplished with a processed kibble diet so we strongly suggest a whole food diet for your dog with this condition. This can be a commercial raw (recommended) or cooked diet, involve a premix with your own raw or cooked meat or a home-prepared diet. If home preparing please research how to do this properly and make sure to add a calcium source like our Seaweed Calcium. Read our article How to Feed Your Dog in the Education Section of our website for more information.

Lion’s Mane Mushroom

This mushroom is a powerful natural brain food that helps to stimulate nerve growth factor (NGF) and regenerate damaged nerve cells.

How much should I give?

Provide 1/2 teaspoon daily per 25 lbs. Divide equally between meals if convenient. Mix with a little water before adding to meal or when in food dish and then blend into food well. If necessary you may safely increase dosage by 50%.

How long should I provide this supplement?

This supplement should be given with every meal for the life of your pet.

Biopreparation F3

This is a highly regarded supplement that can greatly benefit those animals struggling with DM. We recommend the F3+ Forte for this condition. It feeds cells on a cellular level providing thousands of natural nutrients directly into cells without the need for digestion while helping cells to efficiently detoxify. This can be placed in with meals, a little meatball made with a favorite food or in a little water used with a syringe. Follow the recommendations below for the Maintenance Phase for the life of your animal.



Under 15 lbs

1/2 capsule 2x daily

15 - 30 lbs

1/2 - 1 capsule 2x daily

30 - 50 lbs

1 capsule 2x daily

Over 50 lbs

1 capsule 2x daily and you may add a third capsule daily if you desire.

Chia Seed Oil

Myelin sheath is composed largely of fat. By supplying a good source of omega 3 fatty acids you are not only supporting nerve tissue but also helping to reduce inflammation in your animal’s body which can help reduce tissue damage caused by an autoimmune condition. Provide 500 mg of omega 3’s (not total oil content) per 25 lbs from a high quality chia seed oil or fish oil supplement with meals. Provide this supplement for the life of your animal.

GLA from Borage Oil

GLA is a fatty acid that is difficult to get from the diet alone. In addition, many animals do not efficiently synthesize this fatty acid from linoleic acid (LA) especially as they grow older or suffer from degenerative conditions. Because of the anti-inflammatory properties of this fatty acid it can greatly benefit those animals with DM. Provide 240 mg GLA daily divided into morning and evening doses. Most supplements come in capsule form so puncture the end of capsule with pin or knife and estimate dosage as best you can. We will be providing our own organic borage oil in the near future, but as of now you will have to purchase this elsewhere.

Elk Velvet Antler

This is a favorite joint supplement that contains all recommended nutrients for joint maintenance and repair only in a natural, whole food form. Degenerative Myelopathy is not a painful disease but can put extra stress on front knee and shoulder joints. Some veterinarians will prescribe a pain drug, but this can have side effects that interfere with the function of a DM dog - elk antler would likely be a good alternative. In addition, and very importantly, elk antler also contains growth factors that can help energize the body and repair damaged nerve tissue. Provide 1/8 tsp per 15 lbs daily for the life of your animal.

Systemic Enzymes

These are enzymes taken between meals. When this is done the enzymes enter the blood stream where they digest debris and moderate inflammation. Systemic enzymes have also been shown to help break the antibody-antigen bond responsible for autoimmune activity. Use according to instructions on bottle or website.

Whey Protein Isolate

This is a highly bioavailable source of protein that can greatly benefit DM dogs. Biological Value (BV) pertains to the body’s ability to utilize nutrients. Much of the protein found in commercial kibble pet food is low-value and low-protein to boot! Adding whey protein to a lower protein diet, whether that be a kibble or home-prepared diet, can greatly benefit all animals and especially those with DM. Use according to instructions on bag or website.

Acetyl L-Carnitine

This is a supplement that may help to improve neurotransmitter activity in the brain and cellular energy in DM dogs. This is a supplement we recommend for those dogs that are not responding as well to our “Core DM” products and need more help. We do not carry this supplement and recommend 500 mg per 25 lbs daily with meals.


This is the Mother’s first milk that is a vital source of antibodies and blood proteins so important to new born mammals and is considered to be an “anti-aging” supplement for those that take it later in life. Contains anti-inflammatory peptides that help to balance the immune system that can be beneficial in the case of autoimmune conditions like DM. Colostrum also contains important growth factors that can help to increase lean muscle and repair damaged tissue. Use according to instructions on bottle or website with meals.


Exercise is a very important part of a holistic approach to helping an animal with DM. It is very important for maintaining lean muscle, lubricating joints, maintaining the mind-body connection, maintaining lymphatic flow etc. Exercise, such as walking, should be structured for your animal’s conditioning. Your animal should not be pushed to the point of obvious stress and exhaustion.

About Medications

There are no known medications that help with DM. That is why veterinarians believe there is nothing they can do, because that is true. It is also true that there is no “cure” and that this is a condition that has to be managed. However, we don’t promise a cure, and instead we provide your animal’s body with the high-value nutrition needed to heal damaged tissue and rebalance itself for as long as possible.

Common Causes

Nothing “just happens”. There is always a catalyst. Even if your animal is genetically predisposed to DM there is always a “straw that broke the camels back”. Autoimmune conditions are caused or precipitated by an insult to the body, most commonly from a chemical or toxin. This can happen quickly as with autoimmune anemia (IMHA) or over time as with DM. Flea and tick pesticide treatments are a major factor. Reactions will be seen within hours or days of application. Vaccinations are another major factor with reactions generally seen anywhere from days to months after exposure. However, if your animal is more sensitive, household cleaners, lawn chemicals, mosquito fogging exposure and even skunk spray can be a trigger for an autoimmune condition to occur, or to occur at a younger age than in normally might have.

Please keep in mind that if your animal is predisposed to DM or has developed this condition, any exposure to the above will “super-charge” the autoimmune response and the destruction of nerve tissue. Speak with your veterinarian about an exemption from future rabies vaccinations. We recommend avoiding all vaccinations and instead titer and also to avoid any exposure to topical flea and tick pesticide products including collars.

Please Note: The majority of our supplements are basically herbs and whole foods, so a little more or less will not harm your animal. When determining the dosage estimate as best you can for the weight of your animal from our suggested serving sizes.

Ingredients per 1,000 mg (1 gram)

Digestive Plant Enzyme Blend

Bromelain - 350,000 FCCPU
Protease 4.5 - 21,000 HUT
Protease 3.0 - 50 SAPU
Protease 6.0 - 2,000 HUT
Peptidase - 500 HUT
Amylase - 5,000 DU
Lipase - 750 FIP
Glucoamylase - 6 AGU
Cellulase - 350 CU
Hemicellulase - 250 HCU
Diastase - 50 DP
Alpha-Galactosidase - 50 GaIU
Beta-Glucanase - 10 BGU

Probiotic Blend 5 Billion CFU

Equal proportions of the following species of beneficial bacteria:

Lactobacillus acidophilus
Lactobacillus brevis
Lactobacillus lactis
Lactobacillus reuteri
Lactobacillus bulgaricus
Lactobacillus plantarum
Lactobacillus rhamnosus
Lactobacillus salivarius
Lactobacillus casei
Bacillus subtilis DE111®
Bifidobacterium longum
Bifidobacterium lactis
Bifidobacterium bifidum
Streptococcus thermophilus

Natural Prebiotic Dietary Ingredients

Chicory Root Fiber - 50 mg
Fennel Seed - 50 mg

Other Ingredients

Psyllium Seed Husk

Your company is a God send. The way you are able to explain the ingredients in all your products and the proven medicinal purposes each serves is beyond compare. Not to mention how outstanding your customer service and quick shipping is. I have not seen another website like yours and the confidence it inspires in it's customers. There is nothing better one can ask for when dealing with an ailing pet. And because of your products, our guy was able to enjoy an incredible summer of swimming, going for walks, just enjoying life
with only minimal symptoms of DM. My husband and I are forever grateful to you and your husband for your incredible work.
Thank you for your support. (thank you and thank God). It has been a year since Jasper was informally diagnosed with DM. We started your DM core supplements, I think around September. He has since gone on winter vacation with us to Nevada, to escape the harsh winters in Minnesota. Jasper's disease has progressed but much slower than expected, (a previous Boxer of ours only lasted 6 months, without any supplements) so we are encouraged and really attribute this slower progression to your DM Core supplements. Thank you again with all our hearts! Jasper's family
The day before we were leaving on vacation we started giving our 10 year old Rhodesian Ridgeback all 4 of these products that comprise the core degenerative myelopathy protocol. We instructed our dog/house-sitter to continue the routine as prescribed for each of the products. When we came home a week later, we could not believe the difference! The hind leg-shaking was nearly gone and he was running around like a puppy! He was able to get up from laying down with minimal effort compared to the laborious effort he had to put forth prior to starting the degenerative myelopathy protocol. We have been doing this routine for 4 weeks now and he is doing so well. Thank you for this product!!
I just wanted to tell you that after using your nutrition products for a month now, on our beloved GSD who has DMO has showed improvement. We know it will not go away, but at the very least we see a positive improvement. Thank you, we will continue to use your products
I have an almost 13 year old akita (ancient by most standards!) and in July he was officially diagnosed with Degenerative Myelopathy after bringing him to the vet because he started peeing in the house. He was knuckling and dragging his feet, but we assumed it was because he tore his cruciate ligaments (in both hind knees) twice each throughout his life and he had some nasty arthritis - he was pretty old, after all. The vet said there wasn't anything that could be done, that it was fairly common in older dogs and they prescribed us another medication to put him on that turns out could have some nasty long term side effects and we didn't want that at all. He was getting super wobbly and unstable on his feet, would not go up or down stairs at all and just seemed depressed in general. At this point in his life he wasn't super active or anything, but it was obvious it was taking a toll on him. My husband did some research and came across this site and we ordered the DM protocol along with a few other supplements. He is now much happier and the light has returned to his eyes. He is also a lot less lethargic and loves his walks just as much as ever, even if his stamina isn't what it used to be. Within a few weeks of starting this protocol, friends and family who would come visit were saying how great he looked and how much easier he was getting up on his own (still a bit tough sometimes) when he used to struggle badly. Maria has also been super helpful as well, gladly answering any questions or concerns I have. If you have any hesitations about starting this - just go for it. You will not be disappointed. I am looking forward to having my baby boy (old man) with me for at least a little bit longer.
I started my 12 year old Pit Bull Bonnie on the Degenerative Myelopathy Kit a year ago when I first saw signs of weakness in her rear leg’s and was told by her vet that it was due to two damaged disk in her back and that nothing could be done because of her age. That within 8 months to a year she would most likely become paraplegic. The was in june 2014 Bonnie is 13 (july 2015) and doing very well, she gets weak in the rear sometimes but not bad for a girl with a bad back and two bad knees. She can even ran when she wants to, thanks to your help. We couldn’t be happier thanks to your products we are still walking together each day.. Geraldine in MI
In mid-December, my beautiful 12 year old Rhodesian Ridgeback mix, Dancer, had all but been formally diagnosed with Degenerative Myelopathy, an insidious disease which is very much like MS in humans. Her prognosis was very grim. She was fast losing her mobility, stability, coordination, and was experiencing random rear leg paralysis. While all of the symptoms were extremely unsettling for both her and us, the most frightening aspect of all was the paralysis. She has always been so vibrant, and these incidents were clearly scaring her and quickly taking her confidence away. My vet at this time, said there was very little they could do for me other than refer her to a vet who specialized in neurology and who could test her more aggressively.
It was at this time in mid-December 2014, while frantically searching for help, I found your website. When I first found your page on Degenerative Myelopathy, and your suggested treatment plan, I was both hopeful and skeptical. There is, after all very little hope offered when it is suggested a dog may have this condition, as anyone searching the Internet regarding this condition will find. I spoke with Maria and she was very knowledgeable about the condition which immediately impressed me. We spoke at length, and she empathetically offered her support, and let me know that while this may not be the answer, she has seen success with their core plan in both her personal experience, and those of her customers. I decided to order the package and eagerly awaited the arrival. In the meantime, I contacted a holistic vet in my area, who, though would not be able to see her for 2 weeks, said with the chiropractic treatments, a raw food diet, and proper supplements, he could very well be able to improve the quality of her life. When I informed him that I had just purchased the supplements from Pet Health and Nutrition Company, he asked me to forward the information to him so he could review. I did so, and when he got back to me soon after, informed me that this was an excellent direction to take, and that the products were high quality, and that he did not see any reason why starting her on this program while we waited to see him would hurt in any way, and would more than likely provide great help.
Upon visiting our new vet, he advised me on how to incorporate a raw meat diet into her life. Since doing this, and giving her the supplements in the DM package, along with a high quality fish oil and the BioPrep formula, I am so very happy to report that my baby is back! Her coordination and mobility have vastly improved, and the leg paralysis episodes have essentially gone away. While her stamina is not what it used to be, we are able to take her on walks and she does not trip and stumble anymore, which is amazing!
It is now, early March 2015. There is light and life in her eyes and in her step. I know nothing is promised, and I won’t have her forever with me on earth, but I am so grateful to see her enjoying her life again, and I will be happy with every extra day I have with her. As well, I will always and forever be grateful I found your website on that awful day. It gave me hope and guided me to a vet who supports your products and your recommendations, and helped me so much with changing her diet. Ultimately though, it has given me many more precious days with my beautiful angel on earth.
I'm ordering round 2 for Bella because I truly feel these supplements along with the k9 raw food I started her on have been helping with her DM. She is still dragging her feet and im not sure we will ever be able to fix that, but she doesn't seem to be hesitating on the steps as much and she seems a little more stable on her feet. Anything that will keep her up and moving as long as possible, right? I can't thank you enough for these quality products. Stay tuned! Thanks again,
Erin & Bella
I am so grateful to have found this wonderful company. Maria spent almost an hour with me on the phone and was so patient and compassionate. She understands my dog is a member of the family and that I want the very best for him. I have purchased from Pet Health and Nutrition in the past and trust the quality of their products and they were the first place I turned to when my dog was diagnosed with degenerative myelopathy.
My dog was diagnosed with degenerative myelopathy and my vet said there was nothing I could do. So I checked online and found this company. It has only been a couple of weeks and my dog is actually getting better with this protocol. I have high hopes now that I will have him around for much longer than the 6 - 12 months I was told by my vet.
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Dog DM Myelin Supplement Testimonial

These products are truly the answer to a prayer! Just last month it seemed like time with my 14yr old Lab Scooby was sadly coming to an end. After being diagnosed with DM,I felt helpless as I watched him rapidly decline. Standing and walking were difficult for him and he fell often. He lost interest in playing ball and was often incontinent. Desperate to help him, I ordered these products, as nothing was available through veterinary medicine. To my amazement he began improving shortly afterwards. As time went on, my frail, listless buddy grew happy and strong again. After just one month, Scooby stands and walks well, runs after his ball and even JUMPS into the car again! Incontinent episodes are a rarity now. Don't hesitate to try these products. I hope you have as much success with them as I have had. I am so thankful I've been given more time with my best friend!!! Thank you Maria! Joan S.